Scientists was found for the first time in human cells 'quadruple helix' structure of DNA
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Date : 14 Aralık  2013 Cumartesi - 13:58, Category : SCI/TECH


Scientists was found for the first time in human cells 'quadruple helix' structure of DNA

For the first time in human cells 'quadruple helix' structure of DNA was found. Quad helix structure, prevents the spread of cancer cells may lead to the discovery of a new method.




" Nature Genetics " , according to research published in the journal Cambridge University researchers previously thought to have only double-helix structure of DNA in the human entangled came across four DNA strands . More common in rapidly dividing cells of the quadruple helix structure , is thought to be associated with cancer .

Professor of Chemistry Department of the University of Cambridge . Shankar Balasubramanian, quad helix structure or function of the cell is a specific genotype occur when a disturbance occurred , he said. Quad helix structure of DNA and the genetic code holds together the four components that make up a large number of guanine is seen in the region . G- quartet structure was named so .

To find G-quadruplex structures in human DNA antibody proteins expressed their rejection Professor. Balasubramanian, G-quadruplex structures of proteins, antibodies , DNA before cell division revealed that the copy of the show, he said .

G-quadruplex structures when they are imprisoned for drug -like molecules of the cell division process, stating that Prof. affected . Balasubramanian, " G-quadruplex structure of the cell, with the proliferation , thus cancer seen in the uncontrolled sprung associated with . Laboratory we have done in experiments quad helix structure of DNA synthetic molecules confining the cells have divided and proliferation under control have received . These cancerous cells prevent the spread of synthetic molecules can be produced at the first sign "he said.

Balasubramanian, "The Four- helical structure , prevents the spread of cancer cells may lead to the discovery of a new method . These structures by controlling the cancer cells stop dividing , so that we can cure cancer ," he said .

Double-helix structure of DNA , for the first time in 1953 by Francis Crick and James Watson had discovered .



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